Synaptic Transmission Optimization Predicts Expression Loci of Long-Term Plasticity
نویسندگان
چکیده
منابع مشابه
Synaptic Transmission Optimization Predicts Expression Loci of Long-Term Plasticity
Long-term modifications of neuronal connections are critical for reliable memory storage in the brain. However, their locus of expression-pre- or postsynaptic-is highly variable. Here we introduce a theoretical framework in which long-term plasticity performs an optimization of the postsynaptic response statistics toward a given mean with minimal variance. Consequently, the state of the synapse...
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ژورنال
عنوان ژورنال: Neuron
سال: 2017
ISSN: 0896-6273
DOI: 10.1016/j.neuron.2017.09.021